Aims/Introduction: Chronic hyperlipidemia impairs pancreatic b-cell function, referred to as lipotoxicity. We have reported an important role of endogenous reactive oxygen species (ROS) overproduction by activation of Src, a non-receptor tyrosine kinase, in impaired glucose-induced insulin secretion (GIIS) from diabetic rat islets. In the present study, we investigated the role of ROS productio…
Purpose: This study explored the risk factors, cut-off points, sensitivity, specificity, positive predictive values, and negative predictive values of physical performance testing among community-dwelling frail elderly people in Taiwan. Organizing Construct: The empirical measurement of frailty is based on the following five indicators: weight loss, weakness, exhaustion, slow responses, and mi…